Cancer associated with ret - MEN II and III syndromes
Which form of melanoma has the worst prognosis - Nodular melanoma
Most common cause of hematuria - Infection
What type of hemostasis in an intravascular space consists of fibrin, plts, RBCs, and WBCs? - Thrombus
What cardiomyopathy is due to a ventricular outflow obstruction as a result of septal hypertrophy and leads to sudden cardiac death in young athletes? - Hypertrophic cardiomyopathy
Most common Primary tumor metstasis to the bone - Breast
Downward displacement of the cerebellar vermis and medulla compressing the fourth ventricle and leading to obstructive hydrocephalus - Arnold-Chiari Type 2
Most common cause of Meningitis in military recruits Neisseria meningitides
Goodpasture Ag is a component of what type of collagen Type IV
Cardiac muscle regeneration – labile, stable, or permanent? Permanent
Most common cause of Meningitis in adults Strep pneumoniae
Most common Route for infectious arthritis Hematogenous
Cancer associated with alkylating agents Leukemias and lymphomas
What syndrome is due to anti-GBM abs directed against the lung and kidney Goodpasture syndrome
Most causative organism of acute acne Propionibacterium acnes
B-cell neoplasm with CD19, CD20, CD5 (T-cell marker), CD23, and CD-10 negative CLL (B-cell origin)
What vitamin is a component of the enzymes fatty acid synthase and acyl CoA Pantothenic acid
What type of erythema is seen in rheumatic fever Erythema marginatum
Form of coarctation of the aorta assoc with Turner syndrome Preductal (infantile)
Granular deposits of IgG, IgM, and C3 throughout the glomerulus Postinfectious GN
Most common cause of chronic pancreatitis Alcohol abuse
Hereditary angioneurotic edema (AD) produces local edema in organs (GI, resp, skin). What enzyme deficiency causes increased capillary permeability due to release of vasoactive peptides C1 esterase inhibitor
Type of Hypersensitivity Rxn: Circulating Ab-Ag immune complexes deposited in tissue result in neutrophil attraction and the release of lysosomal enzymes Type III hypersensitivity (immune complex)
Disorder of bone remodeling resulting in thick weak bones associated with high-output cardiac failure Paget disease (osteitis deformans)
Which hepatitis B Ag correlates with infectivity and viral proliferatioin HBeAb
Term for RBC fragments Schistocytes
Most common Bone tumor Metastatic
What herpes virus is associated with Kaposi sarcoma HHV 8
What cancer of the male genitourinary system is associated with osteoblastic bony metastasis Prostatic carcinoma
What mushroom poisoning is associated with fulminant hepatitis with extensive liver necrosis Amanita phalloides
Does pancreatic insufficiency result in B12 malabsorption? Yes – panc enzymes begin breakdown of B12-R complex in duodenum
Cardiac tumor associated w/ tuberous sclerosis Rhabdomyoma
Three B’s of adult polycystic kidneys Big, Bilateral, Berry aneurysm
Substance used to test plt’s response in von Willebrand disease Ristocetin
Macro-ovalocytes in the peripheral blood smear are formed from what cell in the bone marrow Megaloblasts
Most common heart defect in down syndrome Endocardial cushion defect
What pattern of inheritance is G-P-PD deficiency X-linked recessive
What ovarian disease involves psammoma bodies – Serocystadenocarcinoma
PKU deficiency - Phenylalanine hydroxylase
Which form of emphysema is associated with alpha-1-antitrypsin deficiency – Panacinar
Most common lobes affected in herpes encephalitis - Temporal lobes
What is the term for the appearance of the kidney in malignant HTN - Flea-bitten kidney (also seen in pyelonephritis) – has petechiae on it’s surface
What organ must metastasize for carcinoid heart disease to occur – Liver
Most common circulating Ig in plasma – IgG
What is the tetralogy of fallot? - VSD, RVH, overriding aorta, and pulmonary stenosis
Call-Exner bodies - Granulosa/thecal cell tumor of the ovary
What gene inhibits apoptosis by preventing the release of cytochrome c from the mitochondria - Bcl-2
Multiple schwannomas, café au lait spots, Lisch nodules, chromosome 17q - Neurofibromatosis I (Neurofibromatosis II is chrom 22q with no Lisch nodules)
Most common Renal cell cancer type - Clear cell
Most common cause of UTI - E coli
What pancreatic islet cell tumor is associated with hyperglycemia, sweating, hunger, confusion, and icreased C-peptide levels? – Insulinoma
What AD GI neoplasia produces multiple adenomatous polyps, osteomas, fibromas, and epidural inclusion cysts - Gardner syndrome
Hep virus that is an enveloped RNA flavivirus - Hep C
Cancer associated with erb-1 - Squamous cell carcinoma of the lung
Most common CNS infection in AIDS – Toxoplasmosis
Most common Benign breast tumor in females under 35 – Fibroadenoma
What lymphoma is associated with bleeding and cryoglobulin precipitation at low temperatures, headache and confusion due to hyperviscosity, IgM M-protein spike on electrophoresis and Russell bodies - Waldenstrom’s macroglobulinemia
What CNS developmental abnormality is assoc with 90% of syringomyelia - Arnold Chiari malformation type 2
Notching of the ribs, seen on CXR in pts with postductal coarctation of the aorta is due to collaterization of what arteries? - Dilation of internal mammary arteries
The 4 DNA oncogenic viruses - HPV, EBV, Hep B, Kaposi sarcoma
Glycogen storage disease due to deficiency of muscle phosphorylase - McArdle’s syndrome
Average volume of RBC – MCV
Cancer associated with sis - Astrocytoma
Most common cause of Meningitis in kids 12 months – 6 years - Haemophilus influenza type B
Neurofibrillary tangles – Alzheimers
Cancer associated with chromium and nickel - Bronchogenic carcinoma
What are the 3 main components of amyloid - Fibrillary protein, amyloid protein, and glycosaminoglycans (mostly hep sulfate)
Painless hyperemic lesions on palms and soles associated with bacterial endocarditis - Janeway lesions
What form of hemophilia is x-linked recessive and is due to a deficiency in factor 9 - Hemophilia B
Cancer associated with vinyl chloride - Angiosarcoma of the liver
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