IMPORTANT FACTS –
IgA nephropathy is the most common form of glomerulonephritis worldwide.
There is male preponderance, peak incidence is in the second & third decades of life.
Two most common clinical presentations are:
● Recurrent episodes of macroscopic hematuria.
● Persistent asymptomatic microscopic hematuria.
Renal histological features of HSP nephritis is strikingly similar to those of IgA nephropathy.
IgA nephropathy is the most common form of glomerulonephritis worldwide.
There is male preponderance, peak incidence is in the second & third decades of life.
Two most common clinical presentations are:
● Recurrent episodes of macroscopic hematuria.
● Persistent asymptomatic microscopic hematuria.
Renal histological features of HSP nephritis is strikingly similar to those of IgA nephropathy.
IgA Nephropathy
IMPORTANT POINTS
Aphemia is a severe form of acute speech apraxia that presents with severely impaired fluency.
Warfarin is not contraindicated in lactating mothers.
Serum lithium level should be checked earliest after 5 days of constant dosing.
Gamma Gandy bodies contain hemosiderin & calcium.
Internucleosomal cleavage of DNA is characteristic of apoptosis.
Most common form of dissociation hysteria is amnesia.
Relapse rate of P.vivax malaria in India is 30%.
Radiation dose of barium enema is equal to 350 X-rays.
Ram's horn & Pseudobillroth appearance on barium studies is a feature of Crohn's disease.
Thiazides decrease positive free water clearance.
Carbohydrate, protein & fat metabolism occur in TCA cycle.
Monosaccharides seperation is by chromatography technique.
Papillary hidradenoma occurs most commonly in anogenital region.
Most common location for performing endomyocardial biopsy is right ventricle.
Earliest immunoglobulin to appear in fetus is IgM.
Cow milk contains soluble radioactive substance - Strontium 90.
Earliest visual field defect in Glaucoma is isopter contraction but paracentral scotomas are more specific.
Aphemia is a severe form of acute speech apraxia that presents with severely impaired fluency.
Warfarin is not contraindicated in lactating mothers.
Serum lithium level should be checked earliest after 5 days of constant dosing.
Gamma Gandy bodies contain hemosiderin & calcium.
Internucleosomal cleavage of DNA is characteristic of apoptosis.
Most common form of dissociation hysteria is amnesia.
Relapse rate of P.vivax malaria in India is 30%.
Radiation dose of barium enema is equal to 350 X-rays.
Ram's horn & Pseudobillroth appearance on barium studies is a feature of Crohn's disease.
Thiazides decrease positive free water clearance.
Carbohydrate, protein & fat metabolism occur in TCA cycle.
Monosaccharides seperation is by chromatography technique.
Papillary hidradenoma occurs most commonly in anogenital region.
Most common location for performing endomyocardial biopsy is right ventricle.
Earliest immunoglobulin to appear in fetus is IgM.
Cow milk contains soluble radioactive substance - Strontium 90.
Earliest visual field defect in Glaucoma is isopter contraction but paracentral scotomas are more specific.
BASIC FACTS
Paracrine regulation refers to factors released by one cell that act on an adjacent cell in the same tissue.
For example, somatostatin secretion by pancreatic islet delta cells inhibits insulin secretion from nearby beta cells.
Autocrine regulation describes the action of a factor on the same cell from which it is produced. IGF-1 acts on many cells that produce it, including chondrocytes, breast epithelium & gonadal cells.
Paracrine regulation refers to factors released by one cell that act on an adjacent cell in the same tissue.
For example, somatostatin secretion by pancreatic islet delta cells inhibits insulin secretion from nearby beta cells.
Autocrine regulation describes the action of a factor on the same cell from which it is produced. IGF-1 acts on many cells that produce it, including chondrocytes, breast epithelium & gonadal cells.
