Sandfly fever Arbovirus
Rift valley fever A virus infecting Sheep
Lassa fever Arena Virus
Glandular fever Ebstein Barr Virus
Bartonneuse fever Rickettsiae Conori
Oroya fever Bartonella
Pretibial fever Leptospirosis
Canicola fever Leptospirosis
Swamp fever Leptospirosis
Seven day fever Leptospirosis
Haverhill fever Streptobacillus Moniliformis
Scarlet fever Streptococci
Pontiac fever Legionella
Undulant fever Malta fever, Brucellos
Gaol fever Epidemic typhus
Classical typhus
5 day fever Trench fever
3 day fever Sandfly fever
Picket fence fever - lateral sinus thrombosis
Breakbone fever - dengue
Step ladder typhoid
Metal fume fever - zinc fumes inhalation toxicity
Nervous fever-typhoid
Roman fever-Malaria
Texas fever - babesiosis
Saturday, 19 April 2014
Fevers
Friday, 18 April 2014
Criteria
Important criterias
1.Halls criteria : Downs syndrome
2.Dukes criteria:
Endocarditis/Heart failure
3.Butchers criteria :mesothelioma
4.Ann Arbours classifiacation :Hodgki.s lymphoma
5.Bismuth classification: tumors of hepatic ductal
system
6.Nazers Index: Wilsons disz
7.Pagets Index : Abruptio placentae
8.Quetlet index: BMI -wt in kg/ht in meter square
9.Ponderial Index: ht in cm/cube root of body wt
in kgs 10.Brocas index : Ht in cms-100
11.Corpulence index : Actual wt/desired wt
12.Milans crjteria: for liver transplant in HCC
13.Mayers n cottons grading system: Subglottic
stenosis
14.Spaldings criteria: abdominal pregnancy
15.GCS/Ransons criteria/APACHE score:
Pancreatitis 16.Ennekings staging : Bone tumors
17. Mc Donald's criteria: Multiple Sclerosis
18.Epworths criteria : Sleep apnea
19.Framminghams criteria/Boston's criteria: CHF
20.Durie salmon system of staging: Multiple
myeloma
21.Lights criteria: pleural effusion 22.GOLD's
criteria :COPD 23.OKUDA staging : HCC 24.Child's
Turcott pug score/MELD/PELD- Cirrhosis
Lymphomas
✅Some stupid mnemonic for lymphomas-
*B*urkitt's: 8;14-->uppercase B looks like an 8; cmyc
Mant*ll*e cell: 11;14-->11;14-->lowercase l looks like a 1 for 11; increased cyclin-d1 so crazy increase in cell cycle rate
*f*ollicular: 14;18-->fourteen starts with f, bcl-2-IgH w/ decreased apoptosis
for fusion proteins/crap i usually remember the prognosis and try to go from there: e.g. mantle cell = awful px, must be a bad mt...it's worse to have a protein forcing unchecked grow vs. lack of checkpoints, so cyclin-d1 is probably involved vs. bcl-2 which is just anti-apoptotic (so i think of it as a slower progression...
for burkitt's lymphoma, just imagine the guy's name is mike burkitt.
Everytime I see or think of burkitt's lymphoma I just remember it's mike burkitt's lymphoma.
mike = c-myc
for mantel cell and follicular:
Mantel: 11-14 because you are proud of your 11-14 year old and put their picture on the mantel
Follicular (has germinal centers): 14-18 because when your kid is 14-18 they start breaking the law and you have to send them to the germinal center
*Hodgkins lyphoma: *
Reed and Sternberg are the names of the two eyes looking at you (reed sternberg cells)
Hodgkins lymphoma is a hedge-hog digging through your chest == systemic syndromes (fever, pruritis, pain with alcohol since it annoys the hedgehog, and contiguous growth since it can't teleport). It is usually in the mediasteinum since thats the only place where a hedgehog can fit.
Prognosis is usually excellent since hedgehogs are commonly killed with poisons.
just memorize this:
Most are cd30+ and cd15+ and associated with EBV
Nodular sclerosing is most common and has lacunar cells and collagen
There can be "nonclassical" hodgkins that are cd120+ and cd45+ but cd30/15 negative. These are often nodular lyphocyte predominant.
*Nonhodgkins lymphomas:*
Burkitt's Lyphoma: 8:14 = *8*urk*14* (14 == it), burkitt is a little kid who likes to blow bubbles (blue cells with bubbles in cytoplasm), and read comics (c-myc), and look up at the starry sky. He ran away to africa and got punched in the jaw and got EBV.
Mantle cell lymphoma: 11:14 = imagine the 11 being a fireplace, the 1 being an OLD MALE and the 4 being a couch that he is about to sit on. Or you can think that 11 looks like a fireplace, and 14 looks like M. The fireplace has FIRE (CD-5 sounds like Fire), and since he is old he likes 'cyclin (bicycling).
Follicular Lymphoma: 14:18 = Four-Lick-ullar lymphoma. There is a 4 in the first one and the 8 looks like a tongue. It also has cleaved cells, which look like tongues. It has bcl-2 *b*e*c*ause it *l*ikes *2* lick.
Diffuse large B-cell lyphomas: most common NHL because it is *diffuse*, children and old adults tend to be*large* so thats who gets it. Older people wear rings and have GI problems so these lymphomas can present with waldeyer ring and GI involvement.
🔟Adult T-cell lymphoma: Some adults are attracted to Teens and give them*flowers* (flower cells in blood). This may happen in *Japan* where they have a thing for loli anime characters. This could result in transmission of *HTLV-1*, which is a STD.
Mycosis fungoides/Sezary syndrome: can present as a really bad fungus-like growth on the skin or *head*(cerebriform nuclei in peripheral blood). and is Cd4+ (4 looks like scissors = scezary)
I have a story like this for every disease and drug.
Will's special
Willis special
Baldwin-Gardner-Willis-Sayé phenomenon
A phenomen relating to tubercle bacilluses.
Willis-Sayé phenomenon
A phenomen relating to tubercle bacilluses.
Willis' circle
The circle of anastomosed arteries at the base of the brain.
Willis' cords
Fibrous cords crossing the superior longitudinal sinus transversely.
Willis' disease I
Historic term for diabetes mellitus.
Willis' disease II
Asthma.
Willis' glands
Corpora albicantia. Obsolete term.
Willis' nerve
The ophthalmic branch of the fifth cranial nerve.
Paracusis of Willis
The ability to hear better in noise.
Baldwin-Gardner-Willis operation
A phenomen relating to tubercle bacilluses.
Willis' pancreas
The processus uncinatus of the pancreas.
Baldwin-Gardner-Willis phenomenon💂
A phenomen relating to tubercle bacilluses.
Beta Blockers
Beta blockers
*🔹Beta blockers are drugs which act against the beta adrenergic
receptors. There are three kinds of adrenergic receptors namely beta1,
beta2 and beta3.
*🔹First generation beta blockers (non-selective beta blockers) :
- Propranolol
- Nadolol
- Timolol
- Penbutalol
- Pindolol
- Oxprenolol
- Alprenolol
*🔹Second generatin beta blockers ( Beta1 selective beta blockers =
Cardioselective beta blockers ):
- Acebutalol
- Celiprolol
- Bisoprolol
- Metaprolol
- Nebivolol (most cardioselective beta blocker)
- Atenolol
- Esmolol
- Betaxolol
*🔹Third generation beta blockers ( These are beta blockers which have
additional vasodilator property ):
- Labetalol and Carvedilol ( act as vasodilators by antagonising
alpha1 receptors on blood vessels)
- Tilosolol ( act as vasodilator by opening up potassium channels)
- Nebivolol and Nipradilol ( generate Nitric oxide )
- Bevantolol, Betaxolol, Carvedilol ( inhibit calcium channels )
- Bopindolol, Carteolol, Celiprolol ( agonists of beta2 receptors )
* 🔹Beta blockers with Membrane stabilising activity (local anaesthetic
activity) :
- Propranolol (most effective)
- Labetalol
- Acebutolol
- Metaprolol
- Pindolol
*🔹 Beta blockers with intrinsic sympathomimetic activity :
- Oxprenolol
- Alprenolol
- Pindolol
- Celiprolol
* Beta blockers which are lipid insoluble ( so they are excreted by
kidney and hence contraindicated in renal failure - LONG ACTING
AGENTS ) :
- Nadolol
- Sotalol
- Acebutalol
- Atenolol
- Betaxolol
- Bisoprolol
- Celiprolol
*🔹 Longest acting beta blocker is Nadolol
*🔹 Shortest acting beta blocker is esmolol.
Ortho notes
Calcutta/Vali: Calves disease = Vertebral body
(central nucleus)
Sunder/Radiologist: Scheurmanns disease = Ring
epiphysis of vertebrae
Fatima/Malik: Freibergs disease = Metatarsal
head
O/T: Osgood schlatters = Tibial tuberosity
Se/Chal: Severs disease = Calcaneal tuberosity
Kar/Nikli: Kohlers disease = Navicular bone
Pahuchi/Fir: Perthes disease = Femoral head
Panna/College: PANNers disease = Capitulum
Ki/Library: Keinbocks disease = Lunate bone
Culture Mediums
3. Loeffler's serum slope & Potassium tellurite blood agar: Corynebacterium diphtheriae
4. Saboraud's dextrose agar: Nocardia
5. Robertson cooked meat medium: All Anaerobic bacteria
6. PLET medium: Bacillus Anthracis
7. Thayer martin or New york city medium: Gonococcus & Meningococcus
8. MacConkey's agar: All Enterobactericeae
9. Selenite F Broth & Tetrathionate broth: Salmonella and shigella
10. Bordet gengue medium: Bordetella pertussis
11. Castneda method: Brucella
12. Cetrimide or dettol agar: Pseudomonas
13. Lowenstein jensen (L-J medium) or dorset egg medium: Mycobacterium Tuberculosis
14. PPLO medium: Mycoplasma
15. skirrow's medium: H.pylori