Myelodisplastic Syndrome

MYELODYSPLATIC SYNDROME Asked Points :
MC cytogenetic change in Myelodysplastic Syndrome in adult - 5q deletion

Cytogenetic change in Myelodysplastic Syndrome in children - Monosomy 7

Common age group affected by Myelodysplastic syndrome - >50

Ringed sideroblast characteristically seen in - Myelodysplastic syndrome

Pawn ball megakaryocytes is characteristic of - Myelodysplastic syndrome

NOT true about Myelodysplastic syndrome - Hypocellular bone marrow

Act by hypomethylation - Decitabine

Harrison Points :
Megaloblastoids are seen in - Myelodysplasia

Ringed sideroblast - Mitochondria encrusted iron

International prognostic scoring system for - Myelodysplasia

Drug used for myelodysplastic syndrome - Lenalidomide

Additional Points :
Treatment of MDS with 5q deletion - Lenalidomide