Thursday 19 June 2014

Amino Acids

Important facts about Amino acids (AA) --

▶ Smallest AA - Glycine
▶ Largest primary AA - Tryptophan
▶ Most basic AA - Arginine (therefore has highest isoelectric pH)
▶ Most acidic AA - Aspartic acid (therefore has lowest isoelectric pH)
▶ AA with imino group - Proline
▶ AA with no amine function - Proline
▶ AA with no chiral carbon (Chirality) , no optical activity & no D-L isomers - Glycine
▶ Flexibility of proteins depend upon - Glycine
▶ AA with best buffering activity at physiological pH - Histidine
▶ Standard AA which can covalently dimerize simultaneously - Cysteine
▶ Most non-polar AA - Phenylalanine
▶ Most polar AA - Glutamine & Asparagine
▶ Absorption of UV light (250-290 nm) - Aromatic AA (Tryptophan > Tyrosine > Phrnylalanine)

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