Signs of Down Syndrome

Halls Ten Signs of Down Syndrome in
Newborns
Neonatal sign
with the % Frequency
(percent of newborns affected)
1.Poor Moro reflex 85
2.Hypotonia 80
3.Flat facial profile 90
4.Upward-slanting palpebral fissures
(eyelid openings) 80
5.Morphologically simple, small round
ears 60
6.Redundant loose neck skin 80
7.Single palmar crease 45
8.Hyperextensible large joints 80
9.Pelvis radiograph morphologically
abnormal 70
10.Hypoplasia of fifth finger middle
phalanx 60