Dose of metronidazole for extra intestinal amebiasis?
800 mg tds × 7-10 d
Dose of metronidazole for intestinal amebiasis?
400 mg tds× 5-7 d
Drug that inhibit pyruvate ferredoxin reductase??
Ntazoxanide
Dose of mebendazole for hookworm infestation ??
200mg/d ×3 days
Dose of albendazole for hookworm infestation ??
400mg single dose
Standard dose of doxycycline ??
100mg BD
Dose of vanco for Rx of MRSA?
500mg QID
Adverse effects of Glucocorticoids
GLUCOCORTICOIDS
G glaucoma
L lunacy(psychotic episodes)
U peptic Ulceration
C cushings habitus
O osteoporosis
C cataracts(post. subcapsular in
children)
O opportunistic infections
R Retention of Na,H2O
(mineralocort.)
T telangectasia
I insulin resistance->
hyperglycaemia
C causes muscle weakness on
withdrawal
O grOwth reatrdation
I by GH inhibition
D delayed wound healing
S supresses HPA axis
#CVA (cerebrovascular accident) synopsis
CVA most common cause
Ischemia >emboli> thrombus> heamorrhage
In Haemorrhage -
Intracerebral> SAH > SDH ~ EDH
Among intracerbral -
Mc cause - HTN
Site - putamen>basal ganglia>thalamus> cerebellum> pons
Among SAH
Cause -
Headtrauma > saccular anneursym > berrys aneurysm > circle of wills
Mc site - anterior cerebral artery circulation
#HYI PORPHYRIA
Most Common Type: Porphyria Cutanea Tarda with basic enzyme deficiency: uroporphyrinogen decarboxylase and Maximum Phototoxicity.
Psychiatric manifestation and Phototoxicity NOT seen: Acute Intermittent Porphyria
Erythropoietic protoporphyria: Ferrochelatase deficiency
Congenital Erythropoietic porphyria: (Only porphyria with A.R)Uroporphyrinogen III synthase
Pseudoporphyria: A [bleep] photosensitivity that clinically and histologically mimics PCT.chronic renal failure treated with hemodialysis,exposure to ultraviolet A (UV-A), Drugs.
Variegate porphyria: protoporphyrinogen oxidase def,cutaneous photosensitivity, systemic symptoms arising from neurologic dysfunction, or both.
Acute Intermittent Porphyria, Varigate Porphyria and Congenital erythropoietic porphyria produce increase in urine prophobilinogen.
Most common site for globe rupture after trauma – Upper nasal quadrant OR Supero-nasal limbus
Weakest point is in the vicinity of canal of schlemm concentric to the limbus.
Most common site of retinal detachment – Upper temporal quadrant
t(x : 17 ) - alveolar soft part tumour
t(x: 18 ) - synovial sarcoma
t(11:14) - mantle cell lymphoma
t(14:18) - follicular cell lymphoma
t(11:18) - maltoma , extranodal marginal zone lymp.
t(15:17) , t (8:21) - AML M3
t(14:4) ,t(14:11) ,t(14:6) , t(14:16) - multiple myeloma
t(8:14) .t(2:8) ,t(8:22) - burkitt's lymphoma
t(2:5) - anaplastic large cell lymphoma
t(3q:v) - diffuse large B-cell lymphoma (v-variable)
t(2:13) - alveolar rhabdomyosarcoma
t(2:16) - myxoid liposarcoma
t(11:22) - pnet , askins tumour( ewings)
t(3:8) - renal adenocarcinoma , mixed parotid tumour
t(6:14) - cystadeno carcinoma of ovary
t(10:17) - papillary thyroid carcinoma
t(x:1) - peadiatric papillary RCC
t(9:22) - philadelphia chromosome
t(12:21) - ALL ( CBF alpha , ETV6)
schizophrenia t(1:11)
PSYCHIATRY Terms-
⛅Agnosia-Inability to recognize a specific sensory stimuli
⛅Apraxia-Inability to perform purposive movement
⛅Alexia-Inability to read
⛅Acalculia-Inabilty to perform arithmetic calculation
⛅Agraphia-Inability to write
⛅Anosmia-Inability to smell
⛅Prospaganosia-Inability to identify a familiar face
⛅Alexithymia-Inability to recognize & describe feelings
⛅Deja vu-sensation of feeling of familiarity.seen im temporal lobe epilepsy
⛅Jamis vu-Sensation of feeling of unfamiliarity
⛅Neologism-Idiosyncratically formed new words which cant be easily understood
⛅Flight of ideas-Rapid speech with rapid change in ideas
⛅Verbigeration-Senseless repetition of same words over & over again.
