Therapeutic Drug Levels

Therapeutic drug levels

Following are some of the drugs that are commonly checked, followed by the normal target levels:
•Acetaminophen: varies with use
•Amikacin: 15 to 25 mcg/mL
•Aminophylline: 10 to 20 mcg/mL
•Amitriptyline: 120 to 150 ng/mL
•Carbamazepine: 5 to 12 mcg/mL
•Chloramphenicol: 10 to 20 mcg/mL
•Desipramine: 150 to 300 ng/mL
•Digoxin: 0.8 to 2.0 ng/mL
•Disopyramide: 2 to 5 mcg/mL
•Ethosuximide: 40 to 100 mcg/mL
•Flecainide: 0.2 to 1.0 mcg/mL
•Gentamicin: 5 to 10 mcg/mL
•Imipramine: 150 to 300 ng/mL
•Kanamycin: 20 to 25 mcg/mL
•Lidocaine: 1.5 to 5.0 mcg/mL
•Lithium: 0.8 to 1.2 mEq/L
•Methotrexate: greater than 0.01 mcmol
•Nortriptyline: 50 to 150 ng/mL
•Phenobarbital: 10 to 30 mcg/mL
•Phenytoin: 10 to 20 mcg/mL
•Primidone: 5 to 12 mcg/mL
•Procainamide: 4 to 10 mcg/mL
•Propranolol: 50 to 100 ng/mL
•Quinidine: 2 to 5 mcg/mL
•Salicylate: 100 to 250 mcg/mL
•Theophylline: 10 to 20 mcg/mL
•Tobramycin: 5 to 10 mcg/mL
•Valproic acid: 50 to 100 mcg/mL

Note:
•mcg/mL = microgram per milliliter
•ng/mL = nanogram per milliliter
•mEq/L = milliequivalents per liter
•mcmol = micromole