Sunday, 20 November 2016

Drugs

drugs used in hypertensive emergency-nitroprusside
nitroglycern
clevidipine
nicardipine
fenoldopam
labeatalol
esmolol
hydralazine
enalaprilat
phentolamine
(mostimp - nifedipine not used..)


Drugs causing disulfiram like action.
Metronidazole
Sulfonamides(CTX)
Cefoperazone
Cefotetan
Cefamandole
Griseofulvin
Moxalactam
Chlorpropamide
Procarbazine
Phenylbutazone
Furazolidone

SOME PRODRUGS AND ACTIVE FORMS
1. LEVODOPA ------------------- dopamine
2. ENALAPRIL ------------------- enalaprilat
3. SULINDAC --------------------- sulfide metabolite
4. BECAMPICILLIN –---------- ampicillin
5. SULFASALAZINE –---------- 5 – aminosalicyclic acid
6. PREDNISONE ----------------- prednisolone
7. ZIDOVUDINE ----------------- zidovudine triphosphate
8. CYCLOPHOSPHAMIDE --- aldophosphamide

DRUGS CAUSING GYNAECOMASTIA
1. spironolactone
2. ketoconazole
3. estrogens
4. testosterone
5. digitalis
6. clomiphene
7. phenytoin
8. griseofulvin
9. calcium channel antagonists
10. reserpine
11. isoniazid
12. methyldopa
13. ethionamide


Drugs causing Fatty liver
1. Antiarrythmics - Amiodarone
2. Antibiotic - Tetracycline ( high-dose, intravenous )
3. Anticonvulsant - Valproic acid
4. Antiviral - Dideoxynucleosides ( eg: Zidovudine ), protease inhibitors ( indinavir, ritonavir )
5. Oncotherapeutics - Asparginase, Methotrexate .

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