Pharma High yield

Mechanism of Action

1-DNA Dependent RNA Polymerase– Rifampcin

2- RNA Dependent DNA Polymerase– Zidovudine

3-Proetin Synthesis Blocker– Erythromycin,     Chloramphenicol & Tetracycline

4-ACE Inhibitor– Captopril

5-Ca Channel Blocker– Nifedipine, Diltiazem

6-COX Inhibitor– Asprin

7-GABA Facilitator– Benzodiazepines

8-Antimetabolites– Methotrexate

9-Loop Diuretics– Frusemide

10-High Ceiling Diuretics– Spironolactone

11-Alteration of bacterial DNA– Choloroquine

12-Inhibition of Viral replication– Amantidine, Acyclovir

13-H1 blocking agent– Mepyramine, Loratadine

14-H2 Blocking agent– Rantidine, Cimetidine, Famotidine, Cyprohaptidine

15-Proton Pump inhibitor– Omeprazole

16-DNA Metabolism Inhibitors– Quinacrine (Mepacrine)

17-Spindle Poison– Vinca, Griesofulvin

18-Folic acid synthesis inhibitor– DDS

19-GABA Inhibitor– Sodium Valproate

20-DNA Synthesis Prevention – Nalidixic Acid

21-Prostaglandin Synthesis Inhibition– Oxyphenbutazone, Ibuprofen

22-Mycolic acid synthesis inhibition– INH

23-Folic acid antagonist- MTX, PAS, DDS & Primethamine

24-Desruption of DNA structure– MNZ

25-Inhibition of cell wall synthesis– Beta lactam antibiotics (penicillin)

26-Release of nor epinephrine– Ephedrine

27-Ergosterol Biosnythesis Inhibitors– Clotrimazole, Miconalzole, Ketoconazole

28-Ach esterase inhibitors– Physostigmine, Neostigmine, Edrophonium, Metrifonate

29-Reverse Transcriptase Inhibitors– Stavudine, zidovudine

30-Inhibition of HIV Protease– Amepranavir

31-DNA Gyrase Inhibitor– Cinoxacin

32-Inhibition of DNA Polymerase-Gossypol

33-NMDA Receptor Antagonist– Amantadine, Ketamine, Dextromethorphan, Memantine & Nitrous Oxide

34-DNA intercalating agent– Daunorubicin, Doxorubicin, Ellipticin & Ethidium Bromide

35-Antim mitotic agent– Amphethenile

36-Alkylating agent- Thiotepa

37-Alpha receptor antagonist- Phentolamine

38-Beta receptor antagonist- Propanolol, Aplrenolol

39-Alpha receptor agonist- Norepinehrine

40- Beta receptor agonist- Isoproterenol & Salbutamol

41-DNA Adduct Formation– Procarbazine

42-Carbonic anhydrase inhibitor- Acetazolamide

43-Phosphodiestrase Inhibitor- Theophylline

44-Thrombin action prevention- Heparin

45-Xanthine oxidase inhibitor- Allopurinol

46-Cholinergic Blockade- Ipratropium

47-Adenosine Deaminase inhibitor- Crisnatapase

48-Immunomodulation– Imiquimod

49-Amino acid transfer interference– Econazole

50-Mast Cell Stabilization– Ketosifen