Myelodysplastic Syndrome

MYELODYSPLATIC SYNDROME
Asked Points :
MC cytogenetic change in Myelodysplastic Syndrome in adult - 5q deletion
Cytogenetic change in Myelodysplastic Syndrome in children - Monosomy 7
Common age group affected by Myelodysplastic syndrome - >50
Ringed sideroblast characteristically seen in - Myelodysplastic syndrome
Pawn ball megakaryocytes is characteristic of - Myelodysplastic syndrome
NOT true about Myelodysplastic syndrome - Hypocellular bone marrow
Act by hypomethylation - Decitabine

Harrison Points :
Megaloblastoids are seen in - Myelodysplasia
Ringed sideroblast - Mitochondria encrusted iron
International prognostic scoring system for -
Myelodysplasia
Drug used for myelodysplastic syndrome -
Lenalidomide
Additional Points :
Treatment of MDS with 5q deletion - Lenalidomide