Risk Factors for Thyroid Carcinoma in Patients with Thyroid Nodule(harrison 18th)
History of head and neck irradiation
Age <20 or >45 years
Bilateral disease
Increased nodule size (>4 cm)
New or enlarging neck mass
Male gender
Family history of thyroid cancer or MEN 2
Vocal cord paralysis, hoarse voice
Nodule fixed to adjacent structures
Extrathyroidal extension
Suspected lymph node involvement
Iodine deficiency (follicular cancer)
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