One liners

1. Cardiotoxic anticancer drug:
Adriamycin /  Doxorubicin, Donorubicin,  Cyclophosphamide,  5 - Fluorouracil

[Dilated Cardiomypathy is caused by.......:-
DoxoRubicin, DonoRubicin ---- (Rubi Dil le gayi)]

2. Digoxin is excreted Through which route (organ): Renal

3. Digitoxin is excreted mainly by which organ:Liver

4. DOC for PSVT:
1. Adenosine
2. Verapamil

5. Effect on calcium levels of Furosemide:Hypercalemia

6. DOC for motion sickness: Hyoscine (transdermal)[Hyoscine aka Scopolamine: 

also Prescribed to 'Prevent' nausea & vomiting caused by Motion Sickness & Vertigo.]

7. Commonest sife-effect of Cisapride is: Diarrhea

8. Common side-effect of Clofazimine: Red brown discoloration of skin

9. DOC for taenia: Praziquantel

10. Drug inhibiting DNA -dependent RNA polymerase in Mycobacteria is: Rifampicin

11. Common  side-effect of Cisplatin: Vomiting

12. Vitamin deficiency noticed with phenytoin use: Folic acid,Vitamin D, and some says vitamin K as well.

13. DOC for lithium induced Polyuria:  Amiloride

14. Concentration of Lidocaine used in Spinal anaesthesia: 5%

15. Local anaesthetic causing methemoglobinemia: Prilocaine

16. Longest acting local anaesthetic: Dibucaine

17. Anaesthetic agent with LEAST analgesic property: Halothane

18. Post spinal headache can last for: 7-10 days

19. Common site of post spinal headache: Occipital

20. Therapeutic index of a drug is an indicator of its: Safety 

21. Common side-effect of Captopril: Dry cough

22. Active metabolite of Enalapril: Enalaprilat

23. Which steroid can be administered by inhalation: Beclomethasone

24. Drug used for heparin induced thrombocytopenia: Argatroban, Lepirudin 

25. Estrogen acts on which receptors:  Cytoplasmic receptors

26. Mydriasis without cycloplegia: Phenyl-ephrine

27. Buprenorphine is: Partial agonist (mu) & antagonist (k) receptors

28. Drug for maintenance therapy for opioids withdrawl: Methadone 

29. DOC for diabetes inspidus: Desmopressin

30. MOA of minoxidil: Potassium Channel OPENER

31. Beta blocker with shortest plasma half-life: Esmolol

32. Pancreatitis is a common side effect of which anti-HIV: Didanosine

33. Anticancer Drug which causes pulmonary fibrosis: Busulfan, Bleomycin.

34. Drug which is used for treating brady-arrythmias: Atropine

35. MOA of Cholestyramine: Binds to bile acids

36. Antifungal which disrupts fungal cell membrane: Griseofulvin

37. Advantage of 3rd generation cephalosporins over 1st and 2nd generation cephalosporins is that they are: Effective against Gram Negative bacteria.

38. Fluoroquinolone banned in India: Gatifloxacin

39. Anti-malarial drug effective in pre-erythrocytic phase in liver is: Proguanil

40. Effect of chloroquine on eye: Bulls eye maculopathy

41. DOC for herpes simplex: Acyclovir

42. ACE inhibitors causes hyperkalemia so they should not be used with:
Potassium Sparing Diuretics

43. Anticoagulant of choice in pregnancy: Heparin

44. Antidote of heparin: Protamine sulphate

45. Profound Analgesia is related to which anaesthetic agent:  Ketamine

46. Best way to prevent hypotension during spinal anaesthesia:  Preloading with Crystalloids

47. Post spinal headache is due to:  CSF leak

48. Agent causing Malignant Hyperthermia: Succinylcholine.

[DOC for MH - Dantrolene]

49. Nerve fibre affected by Local anaesthesia first: Type C

50. Zero order kinetics at higher dose is seen with: Phenytoin

51. DOC for Scabies: 5% Permethrin ('Oral' DOC - Ivermectin)

52. Lithium monitoring is done because of:  Very low Therapeutic Index

53. MOA of pralidoxime: Cholinesterae enzyme reactivator

54. Drug used in BPH: Prazosin, Tamsulosin

55. DOC for Acute Migraine: Sumitriptan

56. Test for Myasthenia Gravis: Edrophonium Test

57. If Theophylline is used with Ciprofloxacin:  Toxicity of theophylline Increases

58. Steroid with equal Gluco-corticoid & mineralocorticoid activity: Hydrocortisone

59. Flumazenil is: Benzodiazepine Antagonist

60. Fomepizole is used in which poisoning: Methanol Poisoning.

61. MC side-effect of chronic use of Phenothiazines is: Tardive Dyskinesia

62. Side effect of Clozapine: Agranuocytosis

63. MOA of Clonidine:  Alpha2 Agonist  & Decreasing Central sympathetic outflow

64. MOA of Digoxin: Na K ATPase inhibition

65. DOC for meningitis due to listeria:  Ampicillin

66. Mode if metabolism of INH: Acetylation

67. Most common side effect of long term use of lithium: Hypothyroidism

68. DOC for MRSA infection: Vancomycin 69. ADH acts on which part of kidney:  Collecting Duct

70. Hemorrhagic Cystitis may be a side effect of: Cyclophosphamide (Rx. Of Hmg Cystitis: MESNA)

71. Metrifonate is used for: Schistosoma 

72. Anticholinergic drug used in peptic ulcer: Pirenzipine

73. Postural hypotension is commoner with which adrenergic blocker: Prazosin

74. Organ toxicity seen with bupivacaine: Cardiotoxicity.

75. LEAST cardiotoxic anaesthetic agent: Isoflurane

76. Dissociative anaesthesia is seen with: Ketamine

77. Sodium Thiopentone is Ultra-short acting due to: Rapid redistribution

78. Dipyradimole acts by inhibiting  PDE-5 79 Beta 1 agonist drug: Dobutamine

80. Beta1 selective adrenergic blocker which can be used as anti-glaucom: Betaxolol

81. Anti-adrenergic drug which crosses blood-brain-barrier minimally: Atenolol

82. Abacavir belongs to which group: NRTI

83. Prostaglandin analogue used in peptic ulcer: E1

84. Prostaglandin analogue used in glaucoma: F2alpha

85. Shortest acting neuromuscular blocking agent: Mivacurium

86. Anaethetic Drug which increase intracranial pressure: Ketamine

87. Anti-epileptic drug which acts by release of the inhibiting transmitter GABA:   Valproic Acid

88. Furosemide & thiazides have similar properties that they both are:  Well absorbed orally

89. MOA of ciprofloxacin: Inhibits DNA gyrase

90. DOC for WPW syndrome: Pracainamide/ Amiodarone

91. Anti-hypertensive which acts by producing NO Sodium: Nitroprusside

92. MOA of Dantrolene:  Sodium Acts on RyR1 receptors resulting in Decreased Calcium.

93. Interstitial nephritis is MC seen with which antibiotic: Methicillin

94. DOC for dermatitis herpetiformis:  Dapsone

95. Neuro-psychiatric symptoms can be seen with: Cycloserine

96. Oral contraceptive failure may be seen with: Rifampicin 

97. MC side-effect of 5-Fluoro-Uracil: Gastro-Intestinal toxicity

98.  MOA of omeprazole: H K ATPase inhibition

99. Prolonged use of steroids may cause: Decrease in bone matrix proteins

100. First drug to be used in anaphylactic shock: Adrenaline (Subcutaneous / IM )